Low-Profile Microtome Blade Holder | Roundfin
1. Dedicated low-profile design — factory-configured for low-profile blades (Feather S35/R35/C35, Leica 818, Erma Patho Cutter R35)
2. CNC-machined 304 stainless steel with fully welded and polished finish for precision alignment and long-term durability
3. Optimized clearance angle geometry for thin, compression-free sections ideal for delicate specimens and serial sectioning
4. Universal dovetail mount compatible with all major microtome brands — Roundfin, Leica, Thermo, Sakura
5. Tool-free blade exchange — blade replacement in under 30 seconds without removing the holder from the microtome
6. Fully autoclavable at 121°C; chemically resistant to xylene, ethanol, and standard lab cleaning agents
Product Overview
The Roundfin Low-Profile Microtome Blade Holder is a dedicated single-profile blade clamping system engineered exclusively for low-profile microtome blades. Factory-configured for precise low-profile blade geometry, it provides rigid, vibration-free blade retention for producing consistent thin sections from paraffin-embedded tissue blocks. Constructed from 304 stainless steel with a fully welded and polished finish, the holder delivers the clearance angle optimization required for delicate specimen sectioning and serial section protocols.
Roundfin Low-Profile Microtome Blade Holder — dedicated clamp for low-profile disposable blades
Key Takeaway: A dedicated single-profile holder factory-calibrated for low-profile microtome blades (Feather S35, R35, C35; Leica 818). The optimized clearance angle and clamping geometry ensure smooth, compression-free sections for delicate and serial sectioning applications.
Technical Specifications
| Parameter | Specification |
|---|---|
| Blade Compatibility | Low-profile microtome blades only (Feather S35, R35, C35; Leica 818; Erma Patho Cutter R35; Roundfin RD-1601A) |
| Material | 304 stainless steel, fully welded and polished |
| Clamping Mechanism | Screw-lock with even pressure distribution; precision-machined blade seat for optimal alignment |
| Microtome Compatibility | Roundfin RD-315, RD-335, RD-355AT; Leica RM series; Thermo HM series; Sakura; universal dovetail mount |
| Section Thickness | 0.5 µm to 60 µm (dependent on microtome) |
| Weight | ~0.45 kg |
| Sterilization | Fully autoclavable at 121°C; chemically resistant for xylene and ethanol cleaning |
Key Features
- Dedicated Low-Profile Geometry — Factory-configured exclusively for low-profile blades with optimized clearance angle for thin, compression-free sections and serial sectioning.
- Precision-Machined Blade Seat — CNC-machined clamping surface ensures perfect blade alignment and even pressure distribution for vibration-free sectioning.
- 304 Stainless Steel Construction — Fully welded and polished for exceptional durability, corrosion resistance, and long service life in high-throughput histology laboratories.
- Universal Dovetail Mount — Standard dovetail interface compatible with Roundfin microtomes as well as Leica RM series, Thermo HM series, and Sakura microtomes.
- Rapid Blade Exchange — Tool-free blade change; insert, clamp, and resume sectioning in under 30 seconds for minimal workflow disruption between specimens.
- Full Autoclavability — Withstands standard autoclave cycles at 121°C; resistant to xylene, ethanol, and paraffin solvents for thorough decontamination.
Applications
- Routine histology and pathology sample-preparation workflows
- Clinical laboratories processing compatible specimens, blocks or slides
- Research and teaching facilities using microscopy and tissue-processing supplies
- Laboratories confirming size, material and equipment compatibility before ordering
Frequently Asked Questions
Can this holder be used with high-profile blades?
No. This holder is factory-configured for low-profile blades only. Using high-profile blades will result in incorrect blade angle, tissue chatter, and potential section compression. For high-profile blades, use the dedicated Roundfin High-Profile Blade Holder, or for labs using both types, the Roundfin DualFit universal holder.
Which Feather blade types are compatible?
This holder is compatible with all low-profile Feather blades including S35 (standard), R35 (routine), and C35 (clean edge for serial sections). It also works with Leica 818 low-profile blades, Erma Patho Cutter R35 blades, and Roundfin RD-1601A blades. Each blade type offers different edge characteristics suitable for varying tissue types and sectioning protocols.
What maintenance is required for optimal performance?
After each use, remove the blade and clean the clamping surfaces with xylene to remove paraffin residue. Wipe with 70% ethanol for disinfection. Periodically inspect the blade seat for paraffin buildup or mechanical wear. The fully welded and polished stainless steel construction requires no lubrication and resists corrosion from routine cleaning agents.
Does this holder fit older microtome models?
Yes. The standard dovetail mount fits most rotary microtomes manufactured since the 1990s, including older Leica RM and Thermo HM models. If your microtome uses a non-standard mount, contact Roundfin for a custom adapter plate — we can engineer a mounting solution for virtually any rotary microtome configuration.
Explore related histopathology consumables or contact Roundfin for configuration, compatibility and quotation details.
