Roundfin DualFit Microtome Blade Holder for Both High-profile and Low-profile Microtome Blade
1. World's first 2-in-1 universal microtome blade holder — compatible with both high-profile and low-profile disposable blades in a single system
2. Quick-toggle profile switching mechanism — change between high-profile and low-profile modes in under 10 seconds without removing the holder
3. 304 stainless steel construction with fully welded and polished finish for corrosion resistance and long service life
4. Dual-mode precision clamping with profile-specific geometry ensures optimal blade angle and vibration-free sectioning for both blade types
5. Universal dovetail mount compatible with Roundfin RD-315/335/355AT, Leica RM series, Thermo HM series, and Sakura microtomes
6. Cost-efficient — one DualFit replaces two dedicated holders, reducing equipment investment and storage requirements
Product Overview
The Roundfin DualFit Microtome Blade Holder is a universal 2-in-1 blade clamping system compatible with both high-profile and low-profile microtome blades in a single holder. This innovative design eliminates the need for separate holders when switching between blade profiles — simply adjust the clamping configuration to match your blade type. Constructed from 304 stainless steel with a fully welded and polished finish, the DualFit holder streamlines histology workflow while maintaining the rigid, vibration-free blade retention required for consistent paraffin sectioning from 0.5 µm to 60 µm.

Roundfin DualFit Microtome Blade Holder — universal 2-in-1 clamp for both high-profile and low-profile microtome blades
Key Takeaway: The only blade holder your histology lab needs. Compatible with both high-profile blades (Feather A35/H35/N35, Thermo MX35) and low-profile blades (Feather S35/R35/C35, Leica 818). Switch between profiles in under 10 seconds without removing the holder from the microtome.
Technical Specifications
| Parameter | Specification |
|---|---|
| Blade Compatibility | Dual-profile: supports ALL major high-profile (Feather A35/H35/N35, Thermo MX35, Leica 819) and low-profile (Feather S35/R35/C35, Leica 818, Erma R35) microtome blades |
| Material | 304 stainless steel, fully welded and polished |
| Profile Switching | Quick-toggle mechanism; switch between high/low-profile in under 10 seconds without removing holder from microtome |
| Microtome Compatibility | Roundfin RD-315/335/355AT; Leica RM series; Thermo HM series; Sakura Accu-Cut; universal dovetail mount |
| Clamping Type | Dual-mode screw-lock with profile-specific clamping geometry; even pressure distribution eliminates vibration |
| Weight | ~0.55 kg |
| Sterilization | Fully autoclavable at 121°C; resistant to xylene, ethanol, and paraffin solvents |
Key Features
- 2-in-1 Universal Design — Compatible with ALL major high-profile and low-profile microtome blades in a single clamping system; eliminates the need for two separate holders.
- Instant Profile Switching — Quick-toggle mechanism switches between high-profile and low-profile modes in under 10 seconds without removing the holder from the microtome.
- 304 Stainless Steel Construction — Fully welded and polished for maximum durability, corrosion resistance, and chemical compatibility in high-throughput histology laboratories.
- Dual-Mode Precision Clamping — Profile-specific clamping geometry with even pressure distribution ensures optimal blade angle and vibration-free sectioning for both blade types.
- Universal Dovetail Mount — Standard interface compatible with Roundfin, Leica, Thermo, Sakura, and most major rotary microtome brands worldwide.
- Cost-Efficient Solution — One DualFit replaces two dedicated holders, reducing equipment investment and freeing up valuable storage space in the histology lab.
FAQ
How does the profile switching mechanism work?
The DualFit features a quick-toggle adjustment mechanism that reconfigures the blade seat geometry between high-profile and low-profile modes. Simply loosen the adjustment screw, slide the clamping plate to the marked profile position, and re-tighten. The entire switch takes under 10 seconds and does not require removing the holder from the microtome, minimizing workflow disruption.
Is sectioning quality comparable to dedicated single-profile holders?
Yes. The DualFit's profile-specific clamping geometry delivers sectioning quality equivalent to dedicated single-profile holders. Each clamping mode is precision-machined to the exact blade angle and clearance requirements of its respective profile. Independent testing confirms no significant difference in section thickness consistency, compression artifacts, or ribbon formation quality compared to dedicated holders.
Which brands of microtome blades are compatible?
The DualFit supports all standard microtome blades on the market. High-profile: Feather A35/H35/N35, Thermo MX35 Ultra/Premier, Leica 819, Sakura Accu-Edge HP, Roundfin RD-1601B. Low-profile: Feather S35/R35/C35, Leica 818, Erma Patho Cutter R35, Roundfin RD-1601A. Any blade conforming to standard 80 x 8 mm dimensions is compatible.
What warranty does the DualFit holder come with?
The Roundfin DualFit Microtome Blade Holder is covered by a 12-month warranty against manufacturing defects. The 304 stainless steel construction is designed for a service life of 5+ years under normal histology laboratory conditions. Roundfin provides comprehensive after-sales support including replacement parts, technical consultation, and compatibility verification for non-standard microtome configurations.








